Medok Lifesciences Private Limited

Rifaximin is a broad-spectrum, non-absorbable antibiotic that acts primarily in the intestines. It is minimally absorbed into the bloodstream, making it ideal for treating infections localized in the gut.

Rifaximin 200 mg tablets are commonly used for:

• Traveler’s diarrhea (caused by E. coli)

• Irritable bowel syndrome with diarrhea (IBS-D)

• Small intestinal bacterial overgrowth (SIBO)

• Hepatic encephalopathy (to reduce ammonia-producing gut bacteria – usually higher doses used)

• Relapsing or chronic gut infections

Ketoconazole 1% w/w Soap is a medicated antifungal soap used to treat and prevent fungal and yeast infections of the skin and scalp. It contains 1% weight/weight of ketoconazole, a broad-spectrum antifungal agent.

• Ketoconazole belongs to the imidazole class of antifungals.

• It works by inhibiting ergosterol synthesis, a vital component of fungal cell membranes.

• This causes the fungal cells to break down and die, eliminating the infection.

Used for treating and preventing:

• Tinea infections (ringworm, athlete’s foot, jock itch)

• Seborrheic dermatitis (dandruff, flaky scalp)

• Pityriasis versicolor (fungal discoloration of the skin)

• Fungal body odor and rashes, especially in moist areas (groin, underarms)

• Recurring fungal infections in humid climates

Ursodeoxycholic Acid (UDCA) is a bile acid-based medication used to treat various liver and gallbladder disorders, especially those involving bile flow problems. The "IP" stands for Indian Pharmacopoeia, confirming quality and formulation standards.

• A naturally occurring bile acid used to:

  • Improve bile flow

  • Protect liver cells

  • Dissolve cholesterol gallstones

• Udiliv

• Ursocol

• Ursofit

• Udihep

• Ursofalk

• 150 mg

• 300 mg

• 450 mg

• 600 mg

Ursodeoxycholic Acid (UDCA) Tablet is a medication primarily used to treat liver and gallbladder disorders, especially those involving bile flow problems. Here's a detailed overview:

• Also known as ursodiol.

• It’s a naturally occurring bile acid.

• Taken in tablet or capsule form to improve bile flow, dissolve certain types of gallstones, and protect liver cells.

• Ursodiol

• Ursofalk

• Udiliv

• Ursocol

• Udihep

• 150 mg

• 300 mg

• 450 mg

• 600 mg

Dosing depends on body weight and condition being treated.

1. Primary Biliary Cholangitis (PBC)

   • Autoimmune liver disease affecting bile ducts.

2. Cholestatic liver diseases

   • Conditions where bile cannot flow from the liver to the duodenum.

3. Gallstone dissolution

   • Especially cholesterol gallstones in patients who can't have surgery.

4. Prevention of gallstones

   • Often after rapid weight loss (e.g., after bariatric surgery).

5. Intrahepatic cholestasis of pregnancy (off-label in some cases)

Piroxicam Dispersible Tablet is a non-steroidal anti-inflammatory drug (NSAID) used to relieve pain, inflammation, and swelling in various conditions, especially in children or people who have difficulty swallowing standard tablets.

• A dispersible tablet is designed to dissolve quickly in water or disintegrate in the mouth.

• Useful for pediatric patients, elderly, or those with swallowing difficulties.

• Piroxicam is an NSAID (Non-Steroidal Anti-Inflammatory Drug).

• Belongs to the oxicam group.

• Works by inhibiting cyclooxygenase (COX-1 and COX-2) enzymes, which reduces the production of prostaglandins—chemicals responsible for pain, swelling, and inflammation.

Amitriptyline Hydrochloride + Methylcobalamin Tablet:

This tablet is a nerve pain relief combination containing:

• Amitriptyline Hydrochloride – a tricyclic antidepressant (TCA) that also works as a nerve pain modulator and sleep aid

• Methylcobalamin (also called Mecobalamin) – the active form of Vitamin B12, essential for nerve repair and regeneration

This combination is primarily used to treat neuropathic pain and related conditions, including:

• Diabetic neuropathy

• Sciatica, nerve compression pain, or trigeminal neuralgia

• Fibromyalgia

• Peripheral nerve disorders due to B12 deficiency

• Chronic pain with sleep issues

This is a combination medication used mainly to treat neuropathic pain. It contains:

• Amitriptyline Hydrochloride – a tricyclic antidepressant (TCA) that also works as a nerve pain modulator

• Methylcobalamin (Methycobalamin) – the active form of Vitamin B12, essential for nerve health and regeneration

This combination is commonly prescribed for:

• Peripheral neuropathy (especially diabetic nerve pain)

• Sciatica, trigeminal neuralgia, fibromyalgia

• Chronic back pain with nerve involvement

• Vitamin B12 deficiency-related nerve pain

• Sleep disturbances associated with chronic pain

Cefpodoxime Proxetil is an oral third-generation cephalosporin antibiotic. The dispersible tablet form is designed to dissolve in water for easy administration, especially in children or those who have difficulty swallowing.

• Common strengths: 50 mg, 100 mg, 200 mg

• Dispersible tablets can be chewed or dissolved in a small amount of water and taken orally.

Cefpodoxime is used to treat a variety of bacterial infections, such as:

• Upper respiratory infections (pharyngitis, tonsillitis, sinusitis)

• Lower respiratory infections (bronchitis, mild pneumonia)

• Urinary tract infections (UTIs)

• Skin and soft tissue infections

• Otitis media (middle ear infections in children)

• Typhoid fever (mild to moderate cases)

Cefpodoxime inhibits bacterial cell wall synthesis, leading to cell death. It is bactericidal and works against both Gram-positive and Gram-negative bacteria.

This is a triple-action anti-inflammatory and pain relief medication, often used in orthopedic, dental, and post-operative settings to manage pain, swelling, and tissue healing.

This combination is commonly prescribed for:

• Joint pain (arthritis, spondylitis)

• Post-surgical inflammation and pain

• Muscle or ligament injuries

• Dental pain or swelling

• Trauma-related swelling and bruising

• Tendonitis and bursitis

• Typically: 1 tablet twice daily (morning and evening), after food.

• Dose and duration depend on condition severity and doctor’s advice.

Cefuroxime Axetil is an oral second-generation cephalosporin antibiotic. It is a prodrug that converts to cefuroxime in the body and works by inhibiting bacterial cell wall synthesis, leading to bacterial death.

• Cefuroxime Axetil Tablets IP 500 mg

• Taken orally, usually twice daily

• Should be taken after food to improve absorption

• Broad-spectrum antibiotic

• Effective against both Gram-positive and Gram-negative bacteria

• Bactericidal (kills bacteria rather than just stopping growth)

Methylcobalamin (also called mecobalamin) is an active form of Vitamin B12. The ER stands for Extended Release, meaning the tablet is designed to release the vitamin slowly over time for longer-lasting effects.

• 1500 mcg (micrograms) per tablet

• Extended release formulation – taken once daily, with or without food

• Available alone or combined with other nutrients (like folic acid, alpha-lipoic acid, or B-complex)

• Peripheral neuropathy (nerve pain or tingling, especially in hands and feet)

• Diabetic neuropathy

• Vitamin B12 deficiency

• Megaloblastic anemia

• Fatigue, weakness, or memory problems due to low B12

• Supportive therapy in neurological disorders like sciatica or trigeminal neuralgia

This is a broad-spectrum antibiotic combination used to treat a variety of bacterial infections. The "IP" indicates that the formulation complies with the Indian Pharmacopoeia standards.

1. Amoxicillin

   • A penicillin-type antibiotic that kills bacteria by inhibiting cell wall synthesis.

2. Clavulanate Potassium (Clavulanic Acid)

   • A beta-lactamase inhibitor that protects amoxicillin from degradation by beta-lactamase enzymes produced by some resistant bacteria.

• 375 mg = 250 mg Amoxicillin + 125 mg Clavulanate

• 625 mg = 500 mg Amoxicillin + 125 mg Clavulanate

• 1000 mg (1 g) = 875 mg Amoxicillin + 125 mg Clavulanate

Always check the strength and take it exactly as prescribed.

• Augmentin

• Moxikind-CV

• Clavam

• Augpen

• Curam

Used to treat infections such as:

• Respiratory tract infections (e.g., sinusitis, bronchitis, pneumonia)

• Urinary tract infections (UTIs)

• Ear infections (otitis media)

• Skin and soft tissue infections

• Dental infections

• Bone and joint infections

Rifaximin is a broad-spectrum, gut-selective antibiotic used mainly for intestinal infections and conditions related to bacterial overgrowth in the gut.

• Rifaximin is a non-absorbable antibiotic, meaning it works locally in the intestines with minimal systemic absorption.

• It is derived from rifamycin but does not enter the bloodstream significantly, making it safer for long-term gut use.

• Xifaxan

• Rifagut

• Rifakem

• Rixmin

Rifaximin 550 mg is commonly prescribed for:

1. Irritable Bowel Syndrome with Diarrhea (IBS-D)

   • Helps reduce symptoms like bloating, loose stools, and abdominal discomfort.

2. Hepatic Encephalopathy (HE)

   • Used to reduce ammonia-producing gut bacteria in patients with liver disease.

3. Traveler’s Diarrhea

   • Caused by E. coli, though the 200 mg dose is usually used here.

4. Small Intestinal Bacterial Overgrowth (SIBO) (off-label)

   • Commonly prescribed in functional gut disorders to reduce bacterial overgrowth.

5. Clostridium difficile relapse prevention (off-label or in combination)

The combination of Trypsin, Chymotrypsin, Paracetamol, and Diclofenac Potassium in a single tablet is a multi-action anti-inflammatory and pain-relief medication. It is typically used to manage pain, swelling, and inflammation associated with musculoskeletal injuries or post-operative recovery.

Here’s a clear and detailed breakdown:

This combination is typically prescribed for:

• Muscle strains or sprains

• Post-operative pain and swelling

• Sports injuries

• Dental or jaw surgery recovery

• Arthritis or joint pain

• Trauma-induced inflammation

Metformin Hydrochloride is an oral anti-diabetic medication used to manage Type 2 Diabetes Mellitus. It belongs to a class called biguanides and is often the first-line treatment for diabetes.

• Available as Immediate Release (IR) or Extended Release (ER/XR) tablets

• Common strengths: 250 mg, 500 mg, 850 mg, 1000 mg

• Type 2 diabetes mellitus – to lower blood glucose levels

• Polycystic Ovary Syndrome (PCOS) – to regulate periods and improve insulin sensitivity

• May also be used for prediabetes or weight management in insulin-resistant patients (off-label use)

Ursodeoxycholic Acid (UDCA) Tablet is a medication primarily used to treat liver and gallbladder-related conditions, especially those involving bile flow problems or cholesterol gallstones.

• Ursodeoxycholic Acid is a naturally occurring bile acid.

• It helps improve bile flow, reduce liver inflammation, and dissolve cholesterol-rich gallstones.

• Ursofalk

• Udiliv

• Ursocol

• Udihep

• Ursodiol

• 150 mg

• 300 mg

• 450 mg

• 600 mg

Dosing is usually based on body weight and the condition being treated.

Ursodeoxycholic acid is used for:

1. Primary Biliary Cholangitis (PBC)

   • An autoimmune liver disease affecting bile ducts.

2. Intrahepatic Cholestasis of Pregnancy

   • A liver disorder during pregnancy (off-label use in some countries).

3. Gallstone Dissolution

   • Specifically cholesterol gallstones in patients not eligible for surgery.

4. Nonalcoholic fatty liver disease (NAFLD) and hepatitis

   • Sometimes used as supportive treatment.

5. Cystic fibrosis-related liver disease

   • To improve bile flow in pediatric patients (under specialist care).

• With food, ideally a fatty meal to improve absorption.

• Usually taken once or twice daily, as prescribed.

• Duration: Often long-term (months to years) in chronic liver disease.

• Typically 10–15 mg/kg/day, divided into 1 or 2 doses.

  • Example: A 60 kg adult may take 600–900 mg/day, depending on the condition.

Aceclofenac, Paracetamol, and Thiocolchicoside Tablets:

Aceclofenac, Paracetamol, and Thiocolchicoside Tablets

These tablets combine three active ingredients to provide effective relief from pain, inflammation, and muscle spasms. Aceclofenac is a nonsteroidal anti-inflammatory drug (NSAID) that reduces pain and inflammation. Paracetamol (acetaminophen) offers analgesic and antipyretic effects. Thiocolchicoside is a muscle relaxant that helps alleviate muscle spasms and stiffness.

• Aceclofenac: 100 mg

• Paracetamol: 325 mg

• Thiocolchicoside: 4 mg

• Management of musculoskeletal pain and inflammation

• Relief of muscle spasms associated with conditions like low back pain, strains, and sprains

• Osteoarthritis, rheumatoid arthritis, and other inflammatory conditions

• Postoperative musculoskeletal pain

Piperacillin & Tazobactam Injection 4.5 gm is a broad-spectrum beta-lactam/ beta-lactamase inhibitor combination antibiotic. It contains Piperacillin, a penicillin-class antibiotic, and Tazobactam, a beta-lactamase inhibitor that extends the antibiotic’s spectrum by inhibiting bacterial enzymes that would otherwise degrade Piperacillin. This combination is highly effective against a wide range of gram-positive, gram-negative, and anaerobic bacteria, including resistant strains.

• Allergic conditions (rhinitis, urticaria, allergic conjunctivitis)

• Appetite stimulant in underweight or malnourished individuals

• Adjunctive therapy in anorexia

• Migraine prophylaxis (in select cases)

• Relief from pruritus and allergic skin conditions

Cefpodoxime Proxetil Tablets are a third-generation cephalosporin antibiotic used to treat a wide range of bacterial infections. Cefpodoxime Proxetil is an orally administered prodrug that is converted in the body to Cefpodoxime, its active form. It works by inhibiting bacterial cell wall synthesis, leading to the death of susceptible bacteria.

Nimesulide + Phenylephrine Hydrochloride Tablets:

This is a combination medicine that includes:

1. Nimesulide – a non-steroidal anti-inflammatory drug (NSAID)

2. Phenylephrine Hydrochloride – a nasal decongestant (alpha-adrenergic agonist)

Together, they are used to relieve pain, inflammation, and nasal congestion associated with cold, flu, and sinusitis.

This tablet is commonly prescribed for:

• Common cold symptoms

• Sinusitis

• Headache with nasal congestion

• Fever with body pain

• Seasonal flu or allergic rhinitis

Methylprednisolone Tablets IP are a prescription corticosteroid (steroid) medication used to treat a wide range of inflammatory and autoimmune conditions. Here's a comprehensive and easy-to-understand guide:

• A synthetic corticosteroid that mimics natural hormones from your adrenal glands.

• Reduces inflammation, suppresses the immune system, and helps with allergic, autoimmune, and inflammatory conditions.

IP stands for Indian Pharmacopoeia, indicating it meets Indian pharmaceutical standards.

• Medrol

• Steron

• Predmet

• Methypred

Usually comes in tablets of:

• 4 mg

• 8 mg

• 16 mg

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A triple-combination topical cream containing:

• Ciprofloxacin – an antibiotic that kills bacteria

• Metronidazole – an anti-protozoal and antibacterial agent (effective against anaerobic bacteria)

• Terbinafine – an antifungal that stops the growth of fungi

• Mixed bacterial and fungal skin infections

• Secondary infected fungal infections (e.g., fungal rash with bacterial superinfection)

• Boils, wounds, or abscesses with suspected mixed infection

• Intertrigo, dermatitis, or eczema with infection

• Clean and dry the affected area

• Apply a thin layer 2–3 times daily

• Do not use for more than 7–10 days without medical advice

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Indomethacin is a non-steroidal anti-inflammatory drug (NSAID) used to reduce pain, inflammation, swelling, and fever. The 75 mg capsule is often an extended-release (SR) or delayed-release formulation, providing longer-lasting effects.

Indomethacin 75 mg is commonly prescribed for:

• Rheumatoid arthritis

• Osteoarthritis

• Ankylosing spondylitis

• Gouty arthritis (acute gout attacks)

• Lower back pain, shoulder pain, and other musculoskeletal disorders

• Postoperative pain and inflammation

Indomethacin inhibits cyclooxygenase (COX-1 and COX-2) enzymes, which are involved in the production of prostaglandins — substances responsible for pain, fever, and inflammation.

Dapagliflozin is an oral anti-diabetic medication. It belongs to the class of drugs called SGLT2 inhibitors (Sodium-Glucose Co-Transporter 2 inhibitors). It helps lower blood sugar by causing excess glucose to be excreted through the urine.

• Dapagliflozin 10 mg tablets

• Usually taken once daily, with or without food

• Commonly available under brand names like Forxiga, Dapanta, etc.

1. Type 2 Diabetes Mellitus – as a single agent or with other medications (e.g. metformin, insulin)

2. Heart Failure (with reduced ejection fraction) – improves symptoms and reduces hospitalization risk

3. Chronic Kidney Disease (CKD) – slows progression and reduces cardiovascular risk

Note: It is not used in Type 1 diabetes or for diabetic ketoacidosis.

Telmisartan + Hydrochlorothiazide Tablet is a combination medication used to treat high blood pressure (hypertension). Here’s a detailed overview:

1. Telmisartan

   • Class: Angiotensin II receptor blocker (ARB)

   • Function: Relaxes blood vessels by blocking the action of angiotensin II, which helps lower blood pressure and reduce strain on the heart.

2. Hydrochlorothiazide (HCTZ)

   • Class: Thiazide diuretic ("water pill")

   • Function: Helps the body get rid of excess salt and water through urine, further lowering blood pressure and reducing swelling.

• The two work synergistically: Telmisartan controls the hormone-driven narrowing of blood vessels, and HCTZ reduces fluid overload.

• Used when one medication alone isn’t enough to control blood pressure

Cefuroxime Axetil is an oral second-generation cephalosporin antibiotic. It is a prodrug that converts to cefuroxime in the body and works by inhibiting bacterial cell wall synthesis, leading to bacterial death.

• Cefuroxime Axetil Tablets IP 500 mg

• Taken orally, usually twice daily

• Should be taken after food to improve absorption

• Broad-spectrum antibiotic

• Effective against both Gram-positive and Gram-negative bacteria

• Bactericidal (kills bacteria rather than just stopping growth)

Methylprednisolone is a steroid medicine that helps reduce inflammation and overactive immune responses in the body.

Doctors prescribe it to treat:

• Allergies (like asthma, hives)

• Joint pain (like arthritis)

• Skin issues (like eczema)

• Autoimmune diseases (like lupus)

• Some breathing, nerve, and eye problems

It mimics natural hormones from your adrenal glands to calm down inflammation and reduce swelling, redness, and immune overreactions.

Usually taken once a day, with food—often 4 to 32 mg per day, depending on your condition.
Important: Never stop suddenly. Tapering is needed (reduce dose slowly).

Short-term (few days):

• Stomach upset, weight gain, mood swings, trouble sleeping

Long-term (weeks/months):

• High blood sugar, weak bones, infections, skin thinning, eye problems

• Type 2 Diabetes Mellitus (as an adjunct to diet and exercise)

• Can be used as Initial therapy when dual control is needed

  • Add-on therapy when glycemic targets aren’t achieved with either agent alone

Methylprednisolone Tablets IP 8 mg contain Methylprednisolone, a synthetic glucocorticoid (corticosteroid) with potent anti-inflammatory and immunosuppressive properties. It is used to manage a wide variety of conditions involving inflammation, allergic reactions, and immune system disorders.

The medicine acts by suppressing the immune response and reducing the release of substances in the body that cause inflammation, providing relief in conditions ranging from arthritis to severe allergies.

Indicated for the treatment of:

• Severe allergic reactions (e.g. asthma, drug reactions)

• Autoimmune diseases (e.g. lupus, rheumatoid arthritis)

• Skin disorders (e.g. dermatitis, psoriasis)

• Inflammatory conditions (e.g. ulcerative colitis, Crohn’s disease)

• Endocrine disorders (e.g. adrenal insufficiency)

• Respiratory diseases (e.g. chronic obstructive pulmonary disease exacerbations)

• As adjunctive therapy in certain infections like tuberculosis, meningitis

• Zinconia‑50 / Zinc acetate tablets: contain zinc acetate, support immune function, wound healing, sometimes used in managing Wilson’s disease by reducing copper absorption. Common side‑effects include stomach upset, metallic taste, and nausea

Methylprednisolone Tablets IP 16 mg are corticosteroid medications used to treat various inflammatory and autoimmune conditions. Here's a comprehensive overview:

• Active Ingredient: Methylprednisolone 16 mg

Methylprednisolone is a corticosteroid (steroid hormone) used to reduce inflammation and suppress the immune system. The “IP” stands for Indian Pharmacopoeia, which means the formulation complies with official Indian quality standards.

This medication is prescribed to treat a wide range of inflammatory and autoimmune conditions, such as:

• Allergic reactions (severe skin rashes, hives, rhinitis)

• Asthma and chronic lung diseases

• Arthritis and joint pain

• Lupus and other autoimmune diseases

• Eye inflammation (e.g., uveitis)

• Skin disorders (eczema, psoriasis)

• Nephrotic syndrome (a kidney disorder)

• Multiple sclerosis flare-ups

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soft gelatin capsules containing Calcium Carbonate, Calcitriol, and Methylcobalamin, along with additional nutrients:

Each softgel typically includes:

• Calcium Carbonate (≈500 mg) – mineral for bone strength

• Calcitriol (0.25 µg) – active vitamin D to enhance calcium absorption

• Omega‑3s (EPA + DHA) – anti-inflammatory support (varies between 90–180 mg EPA & 60–120 mg DHA)

• Folic Acid (60–400 µg) – supports red blood cells and nerve health

• Boron (≈1.5 mg) – helps bone metabolism

combination oral medication containing:

• Rabeprazole Sodium – a proton pump inhibitor (PPI) that reduces stomach acid production

• Domperidone – a prokinetic agent that helps increase stomach motility and relieve nausea

This combination is commonly used to treat:

• Gastroesophageal reflux disease (GERD)

• Acid reflux and heartburn

• Peptic ulcers

• Dyspepsia (indigestion)

• Nausea and vomiting related to delayed stomach emptying

• Rabeprazole blocks the enzyme in stomach lining cells that produce acid, lowering acid levels and allowing ulcers or inflammation to heal.

• Domperidone enhances the movement of food through the stomach and intestines, reducing symptoms like bloating, nausea, and vomiting.

Atenolol & Amlodipine Tablets IP — a commonly prescribed blood pressure medication combination:

This tablet contains two active ingredients:

1. Atenolol (25 mg or 50 mg) – a beta-blocker

2. Amlodipine (5 mg or 10 mg) – a calcium channel blocker (CCB)

Together, they help lower blood pressure, reduce heart workload, and prevent chest pain (angina).

• Hypertension (high blood pressure)

• Angina (chest pain)

• Heart rhythm issues (in some cases)

• Helps prevent heart attacks, stroke, and heart failure due to high BP.

• Atenolol slows your heart rate and reduces the force of contraction → lowers BP and heart stress.

• Amlodipine relaxes blood vessels (widens arteries) → easier blood flow, lowers BP.

Together, they work synergistically: one slows the heart, the other widens blood vessels.

• Usually once daily, at the same time each day.

• With or without food.

• Do not stop suddenly — could cause chest pain or increased BP.